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In cultured endothelial cells, hyperhomocysteinemia has been shown to upregulate monocyte chemotactic protein 1 (MCP-1) and interleukin-8 (IL-8) production, resulting in monocyte adhesion to the endothelium [40]

CCL-11 or Eotaxin-1: an immune marker for ageing and accelerated ageing in neuro-psychiatric disorders

3 SLC7 family members in diabetes pathophysiology 3.1 SLC7 transporter alterations in diabetes Alterations in the expression or function of solute carrier family 7 (SLC7) transporters are implicated in the pathogenesis of diabetes, with effects spanning multiple tissues integral to glucose and amino acid metabolism (71, 72)