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ERK1/2 have been extensively researched, and the ERK1/2 signaling pathway plays a role in both apoptosis induced by oxidative damage and safeguarding against such apoptosis (38, 39)

Fredman G

Parallel intestinal and liver injury during early cholestasis in the rat: Modulation by bile salts and antioxidants

Inactivation of glutathione peroxidase by nitric oxide

In the aging process, it has been noticed that high-molecular protein aggregates accumulate in cells (Davalli et al., 2016)

St-Onge MP, Bosarge A, Goree LL, Darnell B
