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The invention also provides a compound comprising a moiety comprising a vitamin E derivative or a phospholipid derivative, a polyethylene glycol (PEG) or a polyethylene glycol derivative bonded thereto, and a glutathione (GSH) or a glutathione derivative bonded to the polyethylene glycol or the PEG derivative

In accordance with this, pathway analysis of the RNA transcriptome identified oestrogen-mediated S-phase entry, p53 signalling and G1/S checkpoint regulation as canonical pathways significantly modulated in response to GSTO1 knockdown (Supplementary Fig

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