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Neutrophil extracellular traps in inflammatory bowel diseases: implications in pathogenesis and therapeutic targets

USA 109 11522-11527 2012 Homo sapiens (P33527) brenda Hong, Y

Orlowski and Meister found that the ATP-driven reaction that combines glutamate and cysteine to generate -glutamyl cysteine (catalyzed by -glutamyl cysteine synthetase) (Figure 4A) can actually be subdivided into two distinct reaction steps (Figure 4B) (38,54)

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Spanlastics lipid bilayer structure enables the entry of hydrophilic or lipophilic active substances into biological tissue membranes 30

Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study