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No clinical trials or professional guidelines support dual use

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The symptoms can also occur after repetitive activities involving wrist flexion

10.1016/s0928-4257(01)00042-0 84 StaresinicM.PetrovicI.NovinscakT.JukicI.PevecD.SuknaicS.et al (2006)

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Alcohol self-administration, anxiety, and cortisol levels predict changes in delta opioid receptor function in the ventral tegmental area
