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No PCT is required as 5-Amino-1MQ does not affect hormonal pathways

High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells

The team confirmed that 1) CBS protein and H2S levels were elevated in DS cells, 2) that mitochondrial metabolism is impaired in these cells, and 3) demonstrated that CBS inhibition or downregulation improves bioenergetic functions, restores mitochondrial Complex IV activity and consequently improve viability and proliferation rate in DS cells (Panagaki et al 2019)

Polyphenols are one of the largest and most important classes of bioactive chemicals of plants, with two or more hydroxyl groups in the benzene ring [186]

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therefore, the lack of data on lipid metabolism in LC prevents our study from providing a comprehensive picture of metabolic alterations