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g , Top, volcano plot showing relative fold change (log 2 ) in ER-metabolite abundance versus log 10 (P value) from ER-tag HEK293T cells treated with glucose deprivation compared to glucose repletion

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Nystrom E, Bengtsson C, Lapidus L, Petersen K, Lindstedt G

The heightened expression of PKM2 allows for a unique pathway of altered glucose oxidation and enhanced production of lactate in cancer cells and constitute what is referred to as the Warburg effect (see below)

In a recent study of outpatients with ILDs, including IPF, depression score, functional status (as assessed by walk test), as well as pulmonary function, all contributed to the severity of dyspnea

Figure 1 To compile relevant literature for this review, we conducted a structured search of the PubMed, Web of Science, and Scopus databases to identify articles published between January 1990 and March 2025