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This polymeric coating facilitates the movement of liposomes through the mucus layer and improves their ability to penetrate through the enteric epithelium [60]

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ES products are essential for helminth survival/propagation, allowing the parasites to evade immune surveillance

Moreover, for the use of NAC to be clinically relevant, further studies need to examine the potential interference of NAC with the effectiveness of standard chemotherapy, the most suitable time for NAC administration relative to the standard chemotherapy, and the appropriate treatment duration

In this context, maximizing the sample pools, designing studies with more diverse populations, increasing the number of subjects in RCTs, and defining more accurate patient codifies using gold standard diagnostic instruments are common themes for future developments in the field

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