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reported a strong association between reduced DAO activity and the presence of NCGS, although with a reduced number of patients [77,78]

2025;48(10):750-765.[DOI] 36

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Risk and Handling Precautions Risk Tier: MODERATE This rating reflects both peptides' bioactive activity at angiogenic and cytoskeletal signaling pathways in preclinical models, the absence of established human safety profiles for either compound, and the additional handling considerations specific to intranasal formulations

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