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Several studies have shown that H 2 S itself activates angiogenesis in cancer, 161,162,163,164 evidence that was used to develop strategies to promote the release of H 2 S and the activation of angiogenesis under certain pathological circumstances, such as wound healing 165,166 and inflammatory diseases

Importantly, this anti-inflammatory action does not suppress immune function entirely like corticosteroids often do

Glutathione plays a vital role in this process

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