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To investigate the ability to generate a therapeutic effect, the multicellular tumor spheroids were treated with Ru(II)-OH, NP2, or NP4 (10 M Ru) in a 1% or 21% O 2 atmosphere and afterward incubated with a cell live or death stain

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These insights not only enhance our understanding of the metabolic consequences of bactericidal antibiotics but also underscore the intricate relationship between antibiotic action, reactive oxygen species production, and bacterial resilience

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