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Moreover, fatty acid binding protein 7 (FABP7), a marker of immature enteric glia, was significantly upregulated in the myenteric plexus and resulted in a higher ratio of FABP7 to S100 calcium-binding protein B (S100B) expression as compared to controls, signifying a higher proportion of immature EGCs in the ganglionic bowel of HSCR patients [55]

A., Knight, R., Mazmanian, S

PLoS ONE 15:e0236148

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Category 2 of the FDA's 503A list is reserved for bulk drug substances that "raise significant safety concerns." Placement in this category essentially prohibits compounding pharmacies from using the substance to prepare formulations for patients

A single intra-bladder injection of BPC-157 via cystoscopy lead to 100% resolution in 83% of the patients