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REDEFINE 4: The Tirzepatide Test The results that attracted the greatest market attention came from REDEFINE 4, an 84-week open-label Phase 3 trial reported in February 2026, in which CagriSema was pitted directly against tirzepatide 15 mg, the highest approved dose of Eli Lillys Zepbound

International Journal General Medicine

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The same 28-day room temperature rule applies

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Acetylcysteine can then be recommenced once symptoms settle at half rate for 30 minutes and then recommenced as per normal protocol