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However, depressive episodes are not necessary for the diagnosis of BDI

27 Because Fer-1 was more potent than lipophilic or soluble antioxidants, it was hypothesized that its aromatic amine structure may confer a unique profile of radical reactivity upon Fer-1 that is better tuned to the RSL mechanism

Fat mass decreased by 17.0 kg with the combination, compared to 3.4 kg with the placebo, whereas lean mass decreased by 8.4 kg, compared to 2.6 kg

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By situating plant-based nutrition within the broader landscape of thyroidbrain axis dysfunction, this review aims to provide a balanced framework for integrating nutritional strategies with conventional therapy, ultimately improving neurological outcomes and patient quality of life (Figure 1)