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Additionally, they established that according to the WHO definition for MetS, each unit increase in log-transformed IGF-1 concentrations, was associated with a 90.5 % reduction in the risk of MetS [226]
Topical use typically requires 4-8 weeks of consistent application before changes become visible, with maximum benefits at 3-6 months
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These copper ions inhibit type 1 5-alpha reductase by up to 90% in vitro (Sugimoto et al., 1995), reducing local DHT production
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