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Recruited macrophages secrete elevated levels of TNF- and IL-6 through persistent NF-B activation (398, 399)

The unphosphorylated STAT associated with heterochromatin plays a crucial role in preserving HP1 localization and ensuring the stability of heterochromatin

Consistent with mass spectrometry-based binding experiments, CETSA reveals that ML210 engages GPX4 in intact cells but not cell lysates, while chloroacetamide inhibitors interact with GPX4 in both contexts (Figures 3C, 3D, and S3C)

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Switching medications essentially resets your receptor sensitivity