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10.1016/j.devcel.2017.02.016 Dev
Science 339 , 197200 (2013)
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- At 25 to 30 C (warm room): significant degradation within 24 to 48 hours
In addition, NAD + production by the NNT enhance SIRT3-mediated deacetylation and loss of NAD + -dependent deacetylase SIRT3 increases the acetylation of IDH2 at K413 and decreases its enzymatic activity by reducing dimerization, thus regulates mitochondrial redox status and promotes cell tumorigenesis in luminal B breast cancer, 137 and B cell malignancies
doi: 10.1093/jn/135.5.969
