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A Hypothesis Involving Competitive Inhibitions in the Metabolism of Polyunsaturated Fatty Acids

Vilaplana C, Marzo E, Tapia G, Diaz J, Garcia V, Cardona PJ

Oxidative stress happens when there is an imbalance between harmful molecules produced in the body and the bodys ability to get rid of them, potentially causing damage and leading to various diseases

Abiotic stresses generally result in overproduction of reactive oxygen species (ROS) such as singlet oxygen ( 1 O 2 ), superoxide (O 2 ), hydrogen peroxide (H 2 O 2 ) and hydroxyl radical (OH)

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Treatment with combinations of channel blockers, tariquidar (10 M) and Ko143 (10 M), resulted in increased adult worm killing compared to treatments without channel blockers (Table 3)