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Description
After inhalation, the microcapsules predominantly deposit in the alveoli, and released nanoparticles mainly target the antigenpresenting cells (APCs) and induce robust systemic and mucosal immune responses, effectively protecting against SARSCoV2 in mice, hamsters, and nonhuman primates
The presence of LPS induces an increase of neutrophils, macrophages, and cytokines in sputum and bronchoalveolar lavage fluid (BALF) and induces an increase of ROS [56]
A decrease in astrocytic presence in the brain reduces homeostatic support of nervous tissue, while decreased astrocytic synaptic coverage affects synaptic transmission and plasticity, which are translated into depressive symptoms and behaviors 143
10.1038/s41577-020-00478-8 [DOI] [PubMed] [Google Scholar] 327.Grigoletto Fernandes I, Alves de Brito C, Silva Dos Reis VM, Sato MN, Zanete Pereira N
10.1007/s10668-020-00678-1 131 RahdariP.TavakoliS.HosseiniS
Overexpression of human superoxide dismutase inhibits oxidation of low-density lipoprotein by endothelial cells
