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The reported drugs mainly aim at glutamine transporters, glutaminase, aminotransferases, GSH, and NADPH synthesis (Table 1) ( TABLE 1 Pharmacological strategies for inhibiting glutamine metabolism in cancer cells

Oral Glutathione Lower absorption rate Gradual, mild effects May require long-term use Injectable Glutathione Direct bloodstream delivery Higher bioavailability Faster visible skin improvements For aesthetic goals such as skin brightening, injections are typically more effective under professional supervision

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The GPXs mediate the same reaction as catalase, namely, the recycling of hydrogen peroxide into water

Clinical trials and casecontrol articles are included, whereas website articles and other media resources are excluded

10.1242/dev.104596 [DOI] [PubMed] [Google Scholar] Broughton B