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CRISPR-Cas9 in vivo gene editing of KLKB1 for hereditary angioedema

Inhibiting these inflammatory factors can alleviate osteoclast differentiation and the formation of vascular opacities, thereby providing therapeutic benefits for RA

However, most animal experiments utilize supraphysiologic dosage or non-oral routes (e.g

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ROS can directly damage biological structures, including lipids, proteins, and DNA, contributing to cell death, necrosis, and apoptosis (Juan et al., 2021)

doi: 10.7326/0003-4819-104-3-399