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For instance, A oligomers bind CD36/TLR4/TLR6 receptor complexes to activate MyD88-dependent signaling, driving nuclear translocation of NF-B and interferon regulatory factors, thereby initiating transcription of pro-inflammatory cytokines (e.g., IL-1, TNF-) and chemokines [e.g., C-C motif chemokine ligand (CCL)2, CXCL10] (29,30)

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