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Manish Sahni, MD implements a structured monitoring protocol

Eighty-six percent (86%) of ZEPBOUND-treated patients had a maximum tolerated dosage of 15 mg weekly based on their final dose during the double-blind treatment period

Zepbound with GoodRx is around $995 a month, Mounjaro around $1,096

It is unknown whether Zepbound causes such tumors, including medullary thyroid cancer, in humans

But animal-to-human translation is imperfect

A subgroup analysis based on baseline HbA 1c of less than or equal to 8% or greater than 8% revealed no significant treatment subgroup interaction between subgroups for mean HbA 1c change from baseline (eTable 4 in Supplement 2)