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525,526 However, in a randomized controlled trial involving 244 patients with PDPN, 7 treated with venlafaxine developed clinically significant electrocardiogram changes during treatment, making it less preferred in patients with cardiovascular conditions

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Additionally, L-Carnitine supplementation has been associated with improved plasma glucose and ammonia levels, as well as reduced heart rate during exercise [45]

However, other studies showed that protein by itself and without exercise is not effective in improving muscle mass and function in this population [85]