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RNA sequencing To analyse the role of KAT6A in gene regulation in the developing brain, E12.5 dorsal telencephalon tissue was dissected and frozen, and E16.5 cortical neurons were isolated and total RNA was extracted using an RNeasy mini kit (QIAGEN) according to the manufacturers instructions including the optional DNase I digestion step

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It has been found to have some potential-anabolic effects on bone due to stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption (Yamaguchi and Uchiyama 2003

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