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Many identified metabolites, such as those containing sulfur and phenol, are known to be toxic to enterocytes, disrupt intercellular tight junctions (TJ), and stimulate bacterial translocation, all of which support this idea (van der Poll et al., 2017)

Therefore, it is reasonable to assume that CXCL12 Ab cures AGA through AR inactivation, anti-inflammation, and prevention of fibrosis (Figure 2)
10.1016/j.cbi.2015.02.022 22 JiangY.WangY.TanH.YuT.FanX.ChenP.et al (2016)

Howes 2008

The numbers do not add up
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