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I/R-induced heart injury was also relieved by deferoxamine (DFO), an iron chelator 33

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Malcolm Breneil

The primary antibodies used were SIRT1 (1:500, (B-7) sc-74465, Santa Cruz), PGC-1 (1:200, (D-5) sc-518025, Santa Cruz), and -actin (1:10,000, PM053, MBL)

Or look at Tesofensine, which works centrally in the brain by inhibiting the reuptake of neurotransmitters like dopamine, serotonin, and noradrenaline, thereby influencing appetite and energy expenditure