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PEITC inhibited androgen receptor (AR) transcriptional activity in prostate cancer cells by repressing miR-141 expression and miR-141-mediated downregulation of small heterodimer partner (shp), a repressor of AR (46)
The increased inflammatory cytokines have been proposed to be a driver of unsuccessful aging (increased morbidity, degenerative processes, or frailty) and shortened health-span
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Then the end product would be an amide
SOD and CAT are key antioxidant enzymes that maintain redox balance within cells (Pudlarz et al., 2020)
Arvind A, Memel ZN, Philpotts LL, Zheng H, Corey KE, Simon TG
