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While all three genes have multiple AP-1-binding sites, only GCLC has an NFB-binding site

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The 4-phosphopantetheine group also functions in the context of the folate cycle via the cytosolic ALDH1L1 (aldehyde dehydrogenase 1 family member L1) encoded enzyme and the functionally related mitochondrial ALDH1L2

However, it has stronger links to ocular and skin health

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[DOI] [PubMed] [Google Scholar] 276.Tsuchida S