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Recently, multiple case reports and studies indicating safety risks for these medications and their use in patients planning to undergo general anesthesia have been published, as retained gastric contents can lead to intraoperative aspiration

It features a targeted blend of phytonutrients, including berberine, cinnamon bark oil, diindolylmethane (DIM), milk thistle extra

However, because glucagon-like peptide-1 receptor agonists work to slow gastric emptying, a safety concern has been raised in patients undergoing deep sedation or general anesthesia regarding gastric aspiration, and considering their long half-life in the blood, they are difficult to manage in the perioperative period

Safety issues like the black box warning for thyroid cancer risk are also addressed

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