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Ferroptosis, in turn, exacerbates inflammation by releasing oxidized byproducts and iron ions, thereby establishing a detrimental feedback loop involving immunity, metabolism, and ferroptosis within the OA microenvironment (105)
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doi: 10.3389/fcimb.2021.791654 86 SilvaJ
This makes it particularly valuable during the initial adjustment period when skin is adapting to increased cellular turnover
