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Congenital causes are rare and are the result of genetic mutations in genes encoding proteins involved in B12 absorption, transport, and intracellular processing

In silico analysis of UA binding to key EMT markers, including Snail, Slug, and Fibronectin, using quantum-polarized-ligand (QM/MM) docking, shows strong binding affinities and interactions, supporting its potential as an anticancer agent by regulating these markers in breast cancer [1036]

Globally, excess body weight is responsible for about 4 percent of all cancer cases (75)

The excessive accumulation of cholesterol in macrophages activates the inflammasome NOD-like receptor thermal protein domain associated protein 3 (NLRP3), a protein that cleaves IL-1 precursor into its active form and enhances the expression of cytokines [116]

NPLOC4, NPL4 homolog, ubiquitin recognition factor

Ref Type: Generic Veronese FM, Nyc JF, Degani Y, Brown DM, Smith EL: Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora