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Phenomenex, Aschaffenburg, Germany) to remove remaining cells and cell debris

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By inhibiting the production of isoprenoids from the mevalonate pathway, statins prevent the activation of the ras homolog gene family, member A (RhoA)/rho-associated protein kinase (ROCK) in renal macrophages, thereby reducing the assembly of the NLRP3 inflammasome and subsequent production of IL-1/IL-18 (121, 122)

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FitzGerald MP, Anderson RU, Potts J et al: Randomized multicenter feasibility trial of myofascial physical therapy for the treatment of urological chronic pelvic pain syndromes