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Furthermore, hemorrhagic transformation was also lower in frequency for patients who started IV thrombolysis between 1200 and 1800 h compared to those who received treatment between 0000 and 0600 h (Marler et al., 1989)

Diabetologia 57 , 15521560 (2014)

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86 Although complete shunt occlusion would theoretically be ideal, partial shunt attenuation is often sufficient because (a) partial attenuation often results in functional closure 18 (see Figure 61-22), and moreover (b) complete anatomic occlusion may follow in many cases

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