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In other studies, compensatory pathway for GSH synthesis was characterized in yeast and Escherichia coli that lack Gsh1 and GshA [12, 13]

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In the pharmacokinetic analysis, the scheduled sampling times were used for calculation, as the deviations observed were considered not relevant for the analysis purposes, except for one sampling time for one participant

The results of a clinical study further confirmed this observation by showing that patients with nonmetastatic lung cancer harbored loss-of-function mutations in SDH5 128

The morphological features of ferroptosis primarily involve mitochondrial alterations including rupture of the mitochondrial membrane, reduced mitochondrial size with increased mitochondrial membrane densities, and loss of mitochondrial cristae (Li J

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