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Longevity: Lesson from Model Organisms

Meldonium improves mitochondrial morphology and function in MCAO rats In our previous study, target proteins of meldonium were investigated using the HuProt TM human proteome microarray

Diabetologia 60(4):701-8 2017 PMC5342915 Templin AT, Meier DT, Willard JR, Wolden-Hanson T, Conway K, Lin YG, Gillespie PJ, Bokvist KB, Attardo G, Kahn SE, Scheuner D, Hull RL

forty dogs

We consider that this occurred because all of the three cutting-edge medical technologies (antisense oligonucleotides regulating gene expressions, gene therapy using viral vectors, and high-throughput screening of low-molecular-weight compounds) were applied to drug development for SMA in the latter half of the 20th century