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Unlike inactivation of GNPAT (also called DHAP acyltransferase), which results in almost complete loss of ether lipids (Rodemer et al., 2003), knockout of PexRAP in mice results in 5080% decrease in the ether lipid levels (Lodhi et al., 2015)

ACC1 is thought to be the predominant isoform mediating fatty acid synthesis, whereas ACC2, the isoform located near CPT1, is the major regulator of CPT1 activity

As a central component of the canonical Wnt signaling pathway, pry-1 acts as a scaffold to multiprotein destruction complex that negatively regulates the expression of Wnt target genes

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986.Google Scholar DASKIRAN, M

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