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A few examples of efflux transporters include phosphorylated glycoproteins, BCRP, and MDR in both humans and rodents [165, 173, 174]

Some even experience hallucinations and psychosis

Low levels of glutathione can also result from increased demand for glutathione

Additionally, the GAMMA-GLUTAMYL TRANSPEPTIDASE 4 ( GGT4 ) gene was highly upregulated by HL and R treatments (Figure 2), indicating that the GS-OPDA conjugate produced in cytosol, is transported to the vacuole via MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN (MRP) transporters for processing by GGT4 (Dorion et al., 2021

10.1038/sj.jid.5700257 10.1038/sj.jid.5700257 [DOI] [PubMed] [Google Scholar] Schoenfeld JD, Sibenaller ZA, Mapuskar KA et al (2017) O2- and H2O2-mediated disruption of Fe metabolism causes the differential susceptibility of NSCLC and GBM cancer cells to pharmacological ascorbate

Benzyl Alcohol, 1.5%, is present as a preservative and Water for Injection q.s