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have presented a very worthwhile point of view that needs attention (240)

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It should be mentioned, though, that the bulk of current studies is laboratory research or animal models animal clinical trials are still scarce

Pal M, Febbraio MA, Lancaster GIJT

Elevated levels of plasma biomarkers, especially markers of systemic inflammation (interleukin-6 and interleukin-8), epithelial injury (receptor for advanced glycation end products and surfactant protein D) and endothelial injury (angiopoietin 2), as well as dysregulated coagulation markers (low levels of protein C and high levels of plasminogen activator inhibitor 1), have all been associated with adverse SARS results

OECD Good Laboratory Practice principles provide a recognized framework for nonclinical laboratory quality systems where GLP compliance is required