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Description
Potentiates GABA-activated currents associated with downregulated arousal

A shift from small molecules towards biopharmaceuticals in major pharmaceutical companies is likely to lead to increased efforts in developing and evaluating strategies to improve the delivery of large molecules to the brain
Specifically, EGF blocks the upregulation of NOX4 expression in a phosphoinositide 3-kinase (PI3K)-dependent manner

10.1073/pnas.0912437107 [DOI] [PMC free article] [PubMed] [Google Scholar] Benkhoucha M., Senoner I., Lalive P

Endocrine Reviews 1:411, 1980

111, pp
