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doi: 10.1080/07315724.2001.10719063

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Dunn J, Tamaroff J, DeDio A, Nguyen S, Wade K, Cilenti N, Weber DR, Lynch DR, McCormack SE

However, the association between high blood levels of TMAO and atherosclerosis was not observed in the Coronary Artery Risk Development in Young Adults Study (CARDIA) (52) It is not yet clear whether concentrations of choline, betaine, and/or TMAO in the blood can predict the risk for cardiovascular disease
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For those patients in the acute phase, pharmacotherapy provides the potential to improve function, reduce deformity, and stabilize scar progression (5)