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Global trends of the whole-genome duplications revealed by the ciliate Paramecium tetraurelia

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As such, the model was used to simulate how long it would take pharmacologically and toxicologically relevant concentrations of doxorubicin to yield a 70% reduction in GSH concentration, indicative of impaired cellular antioxidant defence, protein binding and cell death 19

SAT1, a metabolic mediator of ferroptotic cell death, is one of the three confirmed genes [117]

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The induction of two biosynthetic enzymes helps Escherichia coli sustain heme synthesis and activate catalase during hydrogen peroxide stress