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Description
HGF binds to its specific receptor c-Met, activating downstream pathways and leading to cell proliferation (Zhao et al., 2022)

Key Points Protein denaturants are the agents causing protein denaturation

CXTD2021001), 2025 Goose Flock Talent Program for Leading Discipline Experts of Wuxi Peoples Hospital (No

Also, because checkerboard-derived FICIs can vary with method (inoculum, endpoint, extract standardization) and may not fully predict in vivo interactions, we recommend completing FICI calculations by retrieving partner-MICs (or performing two-dimensional checkerboards) and confirming promising combinations with time-kill studies or PK/PD modeling prior to claiming clinical-relevant synergy (Bentley, 2024)

Infusion times may last three to four hours or longer depending on individual response

doi: 10.1615/IntJMedMushr.v15.i2.40
