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Some of the peptides, which are typically administered as oral supplements or injections, showed reduced oxidative stress markers in blood and follicular fluid compared to baseline or placebo in trials

(1) This is one reason histamine intolerance during perimenopause may emerge even in women who previously tolerated foods, stress, or hormonal fluctuations without major symptoms
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10.1155/2018/9390810 102 LiuY.WangY
doi: 10.1038/s41418-020-0593-1 48 DAutreauxBToledanoMB