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But the drugs common side effects nausea, vomiting, diarrhea and constipation tended to be worse in individuals over 65, which could exacerbate other underlying health conditions

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Semaglutides (Ozempic and Wegovy) are a class of molecules known as GLP-1 (Glucagon-like peptide 1) receptor agonists that mimic a hormone, GLP-1, in the body to increase the secretion of insulin, lower glucagon, control sugar spikes, and suppress appetite, leading to weight loss

Limitations The major limitations of the studies that are included in this systematic review are the enrollment of healthy subjects and insufficient data in conditions that might affect pharmacokinetics (e.g., kidney dysfunction)