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Plasma concentration of the astrogliosis marker, GFAP, was also increased in patients with moderate to severe COVID-19 (Kanberg et al

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The animals develop seizures, and the authors suggested that the extracellular brain glutamate concentration had become increased, perhaps due to excessive release of glutamate and/or decreased extracellular clearance

Once in the nucleus, ISL1 binds to the promoter region of VEGFR3, enhancing its transcriptional activity and upregulating VEGFR-3 expression
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Braz J Phys Ther

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