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Research shows it restores epithelial integrity after damage from alcohol, NSAIDs, and surgical anastomosis

Although initial clinical assessment pointed toward a potential hematologic malignancy, comprehensive testing, including SPEP, reticulocyte count/fraction, serum folate, and serum vitamin B12, revealed only severe vitamin B12 deficiency, with a level of less than 150, with the presence of IF antibodies

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However, the high proportion observed in the placebo group is likely to have been impacted by the increased use of antihypertensive medications, and fewer participants were able to stop/reduce antihypertensive medication