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Mechanisms of Gegen Qinlian Pill to ameliorate irinotecan-induced diarrhea investigated by the combination of serum pharmacochemistry and network pharmacology

B.DepuyS

Simone et al., 2018

discovered the subclinical MSU crystal deposits in 15% of patients with asymptomatic hyperuricemia by foot/ankle dual-energy CT scans (55)

However, AARS is an exception, which relies on lactate-AMP as an intermediate to directly transfer lactyl group to the lysine residues of target proteins with the assistance of ATP [25, 26] As the most well-studied writer, p300-catalyzed lactylation mainly promotes gene transcription [28,29,30,31,32,33,34,35,36,37,38,39] and maintains normal protein structure and functions [40,41,42,43,44,45]

Available online: 3.Klein R., Klein B.E.K