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& Behrends, C

Explore For people who want a clear diagnostic start instead of guessing at symptoms or self-managing blindly

10.1038/nature13479

Activation of PKC has been determined to lead to inhibition of glomerular endothelial cell function, increased phosphorylation of Erk1/2, decreased activation of endothelial nitric oxide synthase in the glomerulus and endothelial dysfunction may lead to loss of antioxidant and inflammatory effects of nitric oxide, thereby aggravating DKD

Challenges in tolerogenic dendritic cell therapy for autoimmune diseases: the route of administration

J Neurol 255:817