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doi: 10.1080/14653240310003026 [DOI] [PubMed] [Google Scholar] 444

\n\n\n\n Preclinical studies show BPC-157 promotes tendon repair by stimulating fibroblast proliferation, upregulating VEGF-mediated angiogenesis, regulating matrix metalloproteinase activity, activating the nitric oxide pathway, and enhancing growth factor expression in injured connective tissue

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reported lower serum calcium and ferritin, lower HDL cholesterol, and higher LDL cholesterol levels in patients with PG vs controls.20 Premature graying has been linked to early cardiovascular disease, and dyslipidemia may serve as a connecting factor.5 Furthermore, lower vitamin D levels have been reported in patients with PG, although without statistically significant associations.20,27 Regarding copper, lower levels have been observed in PG patients vs controls, but without statistical significance.28,29 Comorbidities Several studies have reported a higher prevalence of atopic diathesis in patients with PG.20,26,30 Das et al